I was denied two times because of my blood pressure was to high at ppdi. I dont have high blood pressure I have never been denied for a study before. After I was denied for a big study at ppdi I imediatly went to a walk in clinic and had a M.D. check my bp and make a print out. My bp was in normal and acceptable range. I had checked my bp everyday at cvs and is always normal ranging from 117 to 130. I brought the reading strait back to ppdi and they would not look at it and not let me in the study after i waited a week for them to just tell me "Im sorry you can't be in the study". What gives? Is it the machines? disorganization ? Trainees screwing up studies for viable candidates? soing just isn't right.. I have spent a grand tring to get into two studies with ppdi I traveled halfway across the country twice to be denied. I lost time, money and much distress with this company. I know now that I cannot count on ppdi . I also overheard other potential voluteers being denied for same reasons and they were completely shocked.
Post by smiling4areason on Apr 15, 2016 21:24:12 GMT -5
You're sitting next to vitals machine, you can see you BP, look at it or ask what it was. It's not like they're just out to get you. I would agree with hiredgoons, the sponsor can set any range they like and if the study drug is known to elevate your BP, they will often want a lower top end to cover this potential. And the same is true if the drug is known to drop BP, they'll want a higher bottom end. Sometimes they have tighter pulse, or narrow ALT, it's all per protocol, there is no normal in a study that is set in stone. Normal outside has very little to do with it. Not what you want to hear, I'm sure, but you need to understand how it really works.
Also, a lot of guys get screening anxiety, which raises pressure, it's just a fact and every time you fail a screening, your anxiety grows next time. Stay well hydrated and find a way to clam yourself down. Good luck.
Post by drakingson on Jun 27, 2016 22:11:25 GMT -5
I had good bp the first year I did studies but as I desired to make more and more money and got more stressed out my bp went up. I also found that the stress of travel caused my bp to elevate. Now I always make sure I arrive a day or two before screening. it can be a pain in the *** but it works. I sometimes take benadryl the night before if I have anxiety. Always get plenty of sleep and try to use very little energy- be a couch potato.
PPD screws people all the time. I've done over 30 studies and never had to do a retest for anything. The day of dosing PPD claimed that I needed to do my ECG over. Just as I was about to get my dose they said I failed my ECG! WTF? I've never failed an ECG. They said some bull about my heart beating too slow. What does an ECG have anything to do with my heart beating too slow. I was pissed. I missed out on an 8k study. If the had told me to get my heart rate up I could have gotten angry and done that. I'm done with PPD. I missed dosing three times and about 3k flying in from Ohio. I am filing a class action law suit to get my travel money and missed study money back. I need others like yourself to complain with me. The more people that we can get the better a case we have contact me.
Post by travelingrat on Jul 17, 2016 16:41:31 GMT -5
over the years i have had issues with certain clinics. but drakingson, i think you do not have a case.
clinics have to follow the parameters that the pharma company researchers have set. i often do "healthy" studies (as a healthy control) at a clinic that does mostly kidney and liver studies for persons with severe kidney or liver problems. the doctor has often phoned the sponsors to tell them that their creatinine level expectations for healthy elderly (my status!) are wildly unrealistic. most of the time, the sponsors just say, keep looking. eventually those few elderly with superb creatinine levels are found. a few times, sponsors have agreed to lower their expectations slightly for an otherwise very healthy volunteer.
my point is that the clinics are REQUIRED to go by the parameters the sponsors have set. if you are out of range right before dosing, they usually have no choice but to reject you.
sometimes at a small clinic, the clinic director or doctor will phone the sponsor and argue for a particular volunteer to be included in the study if they are not too far off the requirements. this rarely happens in the larger clinics such as PPD (in my experience).
i think you would be better off not traveling so far, especially to a large impersonal clinic such as PPD. i am pretty sure that this is not what you want to hear.
also, if you can target some small or mid-sized clinics closer to you and work to cultivate relationships there, my opinion is that that would be to your benefit.
smilingforareason gave a good explanation of what can happen with BP. things like that have happened to most of us over the years. it doesn't mean that your BP was not "normal." it just means it was not in the range the sponsor required.
i wish you good fortune in finding and getting in your next study. for the lab rat pro, some years will always be better (or worse) than others. just put it behind you and keep on moving forward!
Post by SmellYaL8r on Feb 20, 2018 15:57:42 GMT -5
To add to travelingrat, PPD can also get in some serious trouble if they keep repeating your BP until its within the range.. Certain studies might also have stricter guidelines for your own safety. Maybe its a drug that will increase your heart rate even more? etc.
Either way, these studies have to go through the IRB for a reason. Just think about a sick person taking these drugs after us healthy volunteers have Fd with the system. Noooo thank you.
I have the same problem at PPDI. Just screened at ICON in San Antonio & my BP was under 140/90. About a months ago it was 150/100 at PPDI. I was screening for a 12k study & I psyched myself out. It happens. PPD has hundreds of potential volunteers to choose from so they treat you like like cattle. From the 10+ times I screened with them I was only dosed once. It was my first time at ICON and they talked to me like I'm a person & answered my questions. (They were doing a blood screen for TB & I had a positive one before, I had the BCG vaccine as a grew up in Hungary, but I may also have latent TB.)