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Post by respect on Nov 27, 2017 22:30:08 GMT -5
Does this have the capacity to increase orthostatic conditioning?
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Post by respect on Nov 15, 2017 1:56:45 GMT -5
Well my ability to inbox others is no longer available. I didn't know members of Judge Moore's party are against freedom of communication!
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Post by respect on Nov 14, 2017 16:31:35 GMT -5
It is an assault on our community. We are no longer allowed to inbox each other. They have finally crossed the line!
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Post by respect on Nov 14, 2017 9:20:24 GMT -5
This study is broken up into 3 legs back to back. Is each leg and elimination period for the next? So it it more like maximum payout will be 9500. Does anyone know what the projection is for how many will make it to the end. A bonus of 2500 is a big chunk to lose.
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Post by respect on Nov 14, 2017 9:03:57 GMT -5
I think the rules applies. They will be less tolerant. They may also look at it in context of other cardio risk factors reflected in lipid panels, ecgs, inflammation markers; and now diabetic risk vis a vis a1c is also considered a vascular health risk. The IRBs, FDA and ethics board are probably atching their heads. Doctors if they practice ignoring someone health problem could put their research career at risk; do no harm. Time will tell To be noted however is that the Obama administration at its end and now the Trump administration has made it easier for pharma to do their research. They can now fulfill study requirements with smaller groups and less cohorts.
I think a more reasonable approach is for studies to have tier cut off for bp for age and gender the same way they have for other lab values and telemetry. Some centers already apply the age approach to bp. To be noted the change in hypertension definition affects more men than women. Only 19% of women are affected under 45. The data on the same group of men are more troubling.
Most lab rats focus on the systolic, top number when they are excluded but the diastolic new cut off of 80 and above just moved a good 50% into the failure category. This number is less responsive to all the tricks employed when vitals are taken. Even doctors will tell you medication is better at controlling systole than diastole. Diastole occurs when the heart is at rest between beats which is 2/3 of cardiac cycle. To change soing at rest is like asking a possum to play more dead. Diastole is more responsive over time to conditioning so it's inversely proportional to time spent in studies. May be we will have a new terminology in study Non Clinical Significant Hypertension which means for purpose of the study they will ignore values >130/80 and <140/85. Why 85 verses 90 because a 5 point movement in diastole is twice as significant as a 5 point move in systole. Not to bore you but for every 2 point move in the top number the bottom should move only one. So if the top number jumps to 10 above 130 then you should only tolerate 5 point increase in diastole since the heart has to sustain this 5 point jump in pressure 2/3 time longer than the increase pressure of 10 in its contracted state.
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Post by respect on Nov 13, 2017 19:37:43 GMT -5
Big Pharma is trying to con more people like they did with cholesterol to make more money. Before cholesterol 200 and below was considered normal it was 250 and below. The new guidelines resulted in more statin scripts written with billions more for Big Pharma. If you ask your doctor what is your difference in mortality between numbers of 200 and 250 he will most likely throw a blank. Well shift just got serious. The new lower guideline for hypertension is 130/80.That means more Americans will be placed on hypertensive drugs. For subjects it probably mean that many will have to rethink income options. Just like statin studies boomed when nornal cholesterol was revised to 200 expect the same for bp meds. But for many participants they will not be eligible for these studies. Demand and will mean these studies will pay more however. abcnews.go.com/Health/103-million-americans-high-blood-pressure-guidelines/story?id=51121618
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Post by respect on Nov 5, 2017 13:21:53 GMT -5
Since Parexel only allow subjects to participate in 4 studies in a 360 day period, will vct studies count towards the 4?
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Post by respect on Nov 4, 2017 15:57:54 GMT -5
Gerald Williams of Virginia,a veteran, passed away on Friday October 27th. After failing for urine in blood recently several times he discovered he had bladder cancer! The lesson: when you get flagged by a clinic follow through with your doctor.
Pfiser's aggresive approach to screening failure makes so much sense now!
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Post by respect on Nov 4, 2017 15:37:41 GMT -5
The staff has already been trained so when will it be rolled out? That is the million dollar question? Will it be the finger enhanced verisystem? Most likely yes since they are all things technology and it would contain the bottle neck at an already slow check in process!
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Post by respect on Nov 3, 2017 18:33:24 GMT -5
PPD now has vct!
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Post by respect on Nov 3, 2017 14:07:05 GMT -5
This study is for surgically sterile males
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Post by respect on Oct 30, 2017 17:57:49 GMT -5
My main concern would be a reality show flooding the market with too many people trying to get in and driving pay outs down. You made an interesting point.
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Post by respect on Oct 29, 2017 17:26:29 GMT -5
I'm confused. What is Kerri connection to VCT? Any connection could be a conflict of interest as data elements across the platforms could breach confidentially and certainly pose the issue of HIPAA violations!
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Post by respect on Oct 28, 2017 21:14:15 GMT -5
The 3 Ps. Parexel,Pfiser and PPD will hold it against you once a study protocol leads to its discovery. The thing about hep B is that once you get it there is no way to know for sure if you are cured. Sometimes the virus goes dormant and re-emerges at later time;herpes follows a similar pattern. Individuals with multiple partners and those who engage with individuals who have receptive anterior copulation are more likely to contract it. It also explains why it is more common among those who have been incarcerated.
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Post by respect on Oct 14, 2017 10:53:23 GMT -5
All incoming studies will use VCT. The studies posted before verification will not be grandfathered in. The question remains whether later cohorts of those studies will use the finger check system!
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