|
|
Post by carmel on Aug 23, 2018 15:37:02 GMT -5
How do you guys convince yourselves not to worry about side effects? Are there stories out there of little to no side effects during a study, but side effects occurring after a patient was released?
For example, there was a news story of benzodiazepines a few years back and how they now associate it with permanent memory loss if it was used regularly for three months. I guess with study drugs you're far less likely for this to happen since it's short term?
|
|
|
|
Post by idoitforthepong on Aug 29, 2018 11:20:53 GMT -5
I think most of participants, even us "seasoned rats", worry a little bit when dosing for a study...you just wont see it of course. I've done over 30 studies and still have a bit of stress about it...but I worry more about what I miss out in the "real world" by being confined and if family emergencies happen what do I do etc etc. I haven't really had any side effects other than a stray headache or two or just feeling a bit groggy or light headed or stool issues. But some of this can be associated with poor sleep and diet (drugs for breakfast!) that comes with starting a study.
The study you make reference to sounds like a phase 3 or 4 study, where yeah there is more risk as the drug is in your system for long periods of time and things are more experimental. Luckily in our phase one it's usually it's less than a handfull of dosings. And you can always pick and choose your study to the more benign sounding ones...for example stuff that's already FDA approved or good chance of placebo or very small doses etc etc.
|
|
FloridaGirl
Full Member
I am new to Phase 1 clinical trials so I am trying to learn as much as I can .
Posts: 160
Location: Florida
I mainly do: Healthy Studies
# of studies I have done: 3
A little about me: I am just getting started in clinical trials . Became unemployed and was doing small outpatient studies until someone told me about Covance and it has ed up a new world of making money.
So I am trying to do more inpatient studies and am hoping to do even more next year.
|
Post by FloridaGirl on Aug 30, 2018 10:53:27 GMT -5
Of course we worry. I screened for a Alzheimers drug we get one dose but the Dr/PA said med can stay up to three months in yr system so yes concerned but pay good so I am trying to research it and hope that I am ok but yes u can pick and choose. Many drugs are easy like for BP
Diabetes or a drug on market that they are making a generic for.
I always ask the Dr or PA what do they think and they are usually truthful
And then I decide from there.
Like the Alzheimers drug we get release day after dosing so the PA said that would not happen if they thought bad reaction would occur.
|
|
|
|
Post by idoitforthepong on Sept 6, 2018 21:09:15 GMT -5
moxifloxacin is a antibiotic that is used a lot as a "control" in studies, chances are you've taken it if you've done a few studies at spaulding. I was surprised to learn it has neurological and psychological effects as well (according to some quick google searches), but yeah I don't recall that being in the ICF, they did say oh it's just a standard old antibiotic that a kid would take...lol okay if you say so.
Of course we only dose once or twice with the Moxi and antibiotics have to be taken multiple times to build up in your system to to much of anything. Same goes for a lot of what we take, small one time doses of what a patient would take for days on end.
|
|
|
|
Post by carmel on Sept 24, 2018 14:04:52 GMT -5
I think most of participants, even us "seasoned rats", worry a little bit when dosing for a study...you just wont see it of course. I've done over 30 studies and still have a bit of stress about it...but I worry more about what I miss out in the "real world" by being confined and if family emergencies happen what do I do etc etc. Thank you and also to everyone else who replied here. I forget to visit this site. Forums are a thing of the past in most circles. Have you guys thought of reforming somehwere else like on reddit? It'd probably be more active. |
|
|
|
Post by carmel on Sept 28, 2018 13:43:53 GMT -5
Eh. I think im done with studies. I just had a revelation. Like...id prob be making the same money in a year doing studies as i would working part time as a cashier at Dollar Tree. I think if you really do the math, and I mean, really do it properly and not just guess numbers. Like add up all the time it takes you to travel, prepare, and plan.. add to that all the time just thinking about it... in the end you would be better off working a regular job. |
|
|
|
Post by labrat1 on Jun 19, 2021 20:36:16 GMT -5
Eh. I think im done with studies. I just had a revelation. Like...id prob be making the same money in a year doing studies as i would working part time as a cashier at Dollar Tree. I think if you really do the math, and I mean, really do it properly and not just guess numbers. Like add up all the time it takes you to travel, prepare, and plan.. add to that all the time just thinking about it... in the end you would be better off working a regular job. Perhaps true for people who are still able-bodied enough and young enough to get regular employment. Some people are past the age in which their age would NOT be considered in a job. I have a friend who is somewhere in her early 60s, used to be a ballerina when she was younger and now has severe knee problems but works as an actor when she can find roles and other times she applies for seasonal or temporary work and she has applied for several years in a row to work at the U.S. O p e n ( tennis games) in Queens NY doing things such as cashier work or waitressing but as of recent she was told that they would not hire her because they want her to work on her feet not sitting down even though for cashier work, it is possible to have a tall stool to sit on behind the cash register. Certain work just involves being on your feet all the time, lifting things, doing physical things. From the rat's perspective, the most-used or most recruited age group for research studies are people 18 to 45, but that is basically also the age range that people can most easily find work doing soing else. Older people, people past the age of 45 would make better lab rats as far as being more psychologically mature and responsible, also a lot of the ones that are closer to 60 years of age and older would have more time on their hands ( etc) but also, researchers do not want older people because older people often have medical problems that automatically comes with being older. It is a mis match of and demand it seems. Probably it is basically true that considering the cost of travel and hotels to screen for studies and taking a chance on being rejected from studies, a person probably does make the same or a bit more working a regular job. But I recently did a study for a total of $12,000 for a 29 day stay. I think I got paid just a few hundred more than the other rats in my group because I went through some AEs and it lasted a bit longer for me. This is very unusual. |
|
